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  • Ion-conducting and gating molecular mechanisms of channelrhodopsin revealed by true-atomic-resolution structures of open and closed states

Ion-conducting and gating molecular mechanisms of channelrhodopsin revealed by true-atomic-resolution structures of open and closed states

Department: DNICM (НЭОНИКС)
Year: 2025
DOI: DOI https://doi.org/10.1038/s41594-025-01488-7
REFERENCES: D. Zabelskii, S. Bukhdruker, S. Bukhalovich, F. Tsybrov, G.H.U. Lamm, R. Astashkin, D. Doroginin, G. Matveev, V. Sudarev, A. Kuzmin, E. Zinovev, A. Vlasova, Y. Ryzhykau, N. Ilyinsky, I. Gushchin, G. Bourenkov, A. Alekseev, A. Round, J. Wachtveitl, E. Bamberg, V. Gordeliy, Ion-conducting and gating molecular mechanisms of channelrhodopsin revealed by true-atomic-resolution structures of open and closed states, Nat Struct Mol Biol (2025). https://doi.org/10.1038/s41594-025-01488-7

Dmitrii Zabelskii, Adam Round (European X-ray Free Electron Laser GmbH, Germany), Sergey Bukhdruker, Siarhei Bukhalovich, Fedor Tsybrov, Demid Doroginin, Grigory Matveev, Vsevolod Sudarev, Alexander Kuzmin, Egor Zinovev, Anastasiia Vlasova, Nikolay Ilyinsky, Ivan Gushchin, Alexey Alekseev?(Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology, Russia), Gerrit H. U. Lamm, Josef Wachtveitl (Institute of Physical and Theoretical Chemistry, Germany), Roman Astashkin, Valentin Gordeliy (Univ. Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale, France), Ernst Bamberg (Max Planck Institute of Biophysics, Germany), Gleb Bourenkov (European Molecular Biology Laboratory, Germany)

European Synchrotron Radiation Facility (ESRF), beamline ID23-1 (Grenoble, France). The laser flash photolysis setup (MIPT, Dolgoprudny, Russia).